ChromasPro - DNA测序和分析软件
ChromasPro用于将序列读数组装成contigs。有一个图形contig编辑器,显示对齐的色谱图。它还可以进行一般的序列分析,如限制性酶图谱、开放读码框搜索和BLAST提交。
ChromasPro适用于高达几兆的DNA序列组装项目,以及基本的序列编辑和分析。它能够组装来自Sanger测序仪(如ABI)和454和Illumina下一代测序仪的数据,如果有8GB内存的话,至多可组装1,000,000条序列。ChromasPro具有以下特点:
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以Applied Biosystems .ab1, Staden Chromatogram (SCF and ZTR), 454 SFF, FASTA, FASTQ, EMBL, GenBank, SwissProt, GenPept, GCG RSF和纯文本格式打开序列。
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以.ab1、.scf、.fasta和.fastq格式保存序列。
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使用图形界面组装重叠的序列,生成共识,并突出显示模棱两可的地方供编辑。
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使用质量数据自动去除低质量的序列,以提高序列组装。
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使用参考序列作为组装的支架。
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生成限制性位点和片段图,并列出切割、无切割和片段。
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在G+C框架图的帮助下,绘制开放阅读框架图,并一键翻译ORFs。
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打印色谱图、限制性位点和片段图以及开放阅读框架图。
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通过NCBI网站进行核苷酸和蛋白质BLAST搜索。
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通过与ClustalW对接进行多重比对。
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反转和补充序列和色谱图。
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通过准确匹配或optimal排列搜索序列。
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在编辑核苷酸序列时显示翻译。
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进行反向翻译并绘制核苷酸退化图。
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绘制蛋白质的亲水性和抗原性。
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复制色谱图部分的图像,以便粘贴到文档或演示文稿中。
系统要求:
与Windows 7sP1,8,10兼容
【英文介绍】
ChromasPro is for assembly of sequence reads into contigs, with a graphical contig editor which displays aligned chromatograms. It also peforms general sequence analysis such as restriction enzyme mapping, open-reading-frame searches, and BLAST submission.
ChromasPro is suitable for DNA sequence assembly projects up to a few megabases, and basic sequence editing and analysis. It is able to assemble data from Sanger sequencers such as ABI, and 454 and Illumina next-generation sequencers, with up to 1,000,000 sequences if 8 Gb RAM is available. ChromasPro has the following features:
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Open sequences in Applied Biosystems .ab1, Staden Chromatogram (SCF and ZTR), 454 SFF, FASTA, FASTQ, EMBL, GenBank, SwissProt, GenPept, GCG RSF and plain text formats.
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Save sequences in .ab1, .scf, .fasta and .fastq formats.
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Assemble overlapping sequences using a graphical interface, generate a consensus and highlight ambiguities for editing.
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Use quality data to automatically remove low quality sequence for improved sequence assembly.
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Use a reference sequence as a scaffold for assembly.
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Generate restriction site and fragment maps, and list cutters, non-cutters and fragments.
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Map open reading frames, aided by a G+C frame plot, and translate ORFs with one click.
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Print chromatograms, restriction site and fragment maps, and open reading frame maps.
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Perform nucleotide and protein BLAST searches through the NCBI web site.
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Perform multiple alignments by interfacing with ClustalW.
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Reverse & complement sequences and chromatograms.
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Search for sequences by exact matching or optimal alignment.
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Display translations when editing nucleotide sequences.
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Perform reverse translations and plot nucleotide degeneracy.
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Plot hydrophilicity and antigenicity of proteins.
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Copy an image of a chromatogram section for pasting into documents or presentations.
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